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Research demonstrates that senescent cells upregulate FOXO4 expression as a survival mechanism, using the transcription factor to sequester p53 in the nucleus and prevent its pro-apoptotic signaling cascade
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TB-500 has demonstrated similar positive results across various experimental paradigms
Therefore, administration of this drug causes gastrointestinal side effects such as nausea or weight loss
Our purpose is not to endorse or suggest the use of specific therapies, but to provide information about the evidence, or lack thereof, along with potential risks/benefits of various treatment modalities
No therapeutic, diagnostic, or dosing claims are made
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