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3 of 3: Exenatide (BYETTA, BYDUREON) Phonetic pronunciation: ex EN a tide / bye A tuh / by DUR ee on Mnemonic: X in a Tide (Pod) Year of release: 2005 Price range: $740$950 either formulation FDA-approved for: Type 2 diabetes Mechanism: GLP-1 receptor agonist Dynamic interactions: Glucose lowering Kinetic interactions: Delayed gastric emptying, otherwise none in a bubble The structure of - en atide GLP analogs is based on ex en din, a naturally occurring peptide derived from lizard venom
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Paradoxically, this increase has been associated with improved all-cause mortality as well as cardiovascular mortality, according to a post hoc analysis of the PROactive trial (259)
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