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These medications also improve glycaemic control by enhancing insulin secretion in response to meals and suppressing glucagon release

First experiment: (Ethanol study), twenty-four male C57BL/6 N mice aged 1214 weeks were purchased from NIAAA and were kept in an environment with controlled temperature (23C 1 C) and a 12-h light/12-h dark cycle

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doi:10.1016/j.pharmthera.2009.11.005

23 The STEP-HFpEF and STEP-HFpEF-DM trials randomised patients with HFpEF and an LVEF 45% to oral semaglutide or placebo