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The brain and other organs (heart, lung, liver, pancreas, spleen, and kidney) of mice treated with weekly 0.5 g/g semaglutide were fixed via cardiac perfusion with phosphate-buffered saline (PBS), dissected out and postfixed at 4 C in 4% paraformaldehyde (PFA 4%) for at least 24 h and cryoprotected in 30% sucrose solution overnight

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J Mazandaran Univ Med Sci

Tirzepatide is a synthetic peptide engineered to activate receptors for two naturally occurring incretin hormones: glucose-dependent insulinotropic polypeptide, or GIP, and glucagon-like peptide-1, or GLP-1

doi: 10.3390/ijms251910606 115 YunusM