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These medications, originally developed for diabetes management, improve multiple metabolic pathways implicated in metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as nonalcoholic fatty liver disease (NAFLD)

GLP-1 treatments approved by the FDA come with a steep wholesale acquisition cost of over $12,000 per year

Clinical trials of tirzepatide extended up to 72 weeks, with continued weight loss throughout the study period

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Additionally, semaglutide slows gastric emptying, prolonging the sensation of fullness and reducing the frequency of hunger signals