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doi: 10.2337/db19-1004-P 46 MosenzonO.WiviottS
Newer medications like Wegovy and Mounjaro are now preferred, with Mounjaro receiving broader NICE approval (TA1026) in 2024
EQUIP showed modest BP and lipid improvement, but cardiovascular safety is uncertain [16]
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If your plan has one: Standard prior authorization for Wegovy will be denied Appeals are usually unsuccessful (exclusions are plan design decisions) Alternative coverage pathways may exist (cardiovascular or sleep apnea indications) If your plan excludes weight loss coverage, Wegovy has a cardiovascular indication and Zepbound has a sleep apnea indication
This higher dose did produce more gastrointestinal side effects, but the additional weight loss was statistically significant
