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The dose-response relationship favors IV delivery
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Gene expression studies show it activates DNA repair genes and tumor suppressors like p53 while dialing down genes linked to metastasis
The primary proteins involved in drug binding are albumin, alpha-1 acid glycoprotein (AAG), and serum-binding globulins (Succari et al
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Nonetheless, the FDA is currently considering inclusion of both of these forms to its 503A bulk drug list
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