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Treatment with 3 mg liraglutide for 20 weeks reduced appetite and energy intake, resulting in a significant weight loss (7.2 kg) in a large, RCT in people with obesity [15]

Originally developed to treat type 2 diabetes, semaglutide works by stimulating a hormone called GLP-1, which plays a role in regulating blood sugar and insulin levels

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Prior to this, the two drugs had only been compared in studies evaluating their efficacy against a placebo