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The changes in lactate in ME/CFS are consistent with the presence of energetic stress and mitochondrial dysfunction
Les taches brunes sont souvent lies une inflammation passe : acn, soleil, irritation
doi: 10.18520/cs/v112/i09/1839-1854 159 PorczaLMSimmsCChopraM
Both have generally well-tolerated safety profiles in healthy patients without contraindications
One study noted that after surgical stress, monocytes had increased markers of mitochondrial damage but reduced expression of PINK1 and Parkin (key mitophagy proteins), suggesting defective clearance of bad mitochondria (64)
Because tumor growth also depends on new blood vessels, several reviews describe this as a theoretical concern that has not been resolved in humans (Sehgal et al., Pharmaceuticals, 2025)
