Disproportionality analysis A sequential approach was adopted to systematically address major confounders: (1) An exploratory disproportionality approach comparing GLP-1RAs with all other drugs reported in the FAERS database, using venlafaxine as the positive control and empagliflozin/orlistat as the negative control
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Adult patients with type 2 diabetes at high risk for cardiovascular events (N=9340) were randomized to receive once-daily Victoza (0.6 mg-1.8 mg once daily with all patients being titrated to 1.8 mg once daily) or placebo
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