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[32] The enzyme used in the present invention was commercially available immobilized lipase Novozyme 435 (Novozymes)
Gastrointestinal effects Nausea is the most common side effect
Phase 3 trial results released in December 2025 showed participants lost an average of 28.7% of their body weight (about 71 pounds) over 68 weeks, the highest weight loss reported for any obesity medication to date
Using the same spot repeatedly causes lipohypertrophy, which is a buildup of hardened fatty tissue under the skin
In 2013, Phongmitr et al
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