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(1) This may upregulate growth hormone (GH) synthesis, which is a hormone with catabolic potential towards fat cells, and also may possess anabolic potential via a mediator called insulin-like growth factor 1 (IGF-1) The research suggests that it may produce rapid, concentration-dependent, pulsatile GH elevations, yielding GH pulses roughly 20- to 30-fold above basal values and potentially close to other GHSs such as GHRP-6 and GHRP-2

ZA and DJM are principal investigators and made contributions to the design of the study, acquisition (DJM) and interpretation of the data, and revision of the manuscript

Ashley Koff, RD 00:23:39 Yeah

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They explain why recovery may feel slower on GLP-1 therapy, but they do not represent permanent limitations