Common adverse effects are predominantly gastrointestinal and typically emerge during dose escalation: Nausea (affecting 2050% of users initially) Vomiting and diarrhoea Constipation Abdominal pain and bloating Reduced appetite (therapeutic effect but may be excessive) Fatigue and headache Injection site reactions (redness, swelling or itching) These effects usually diminish over several weeks as the body adjusts
Compounded semaglutide contains the same active pharmaceutical ingredient as brand-name products
While GLP-1 receptor agonists like semaglutide have shown some anti-inflammatory properties in animal studies, these effects are not primary focus in human treatment and have not been proven to benefit MS patients specifically
When they do occur, they are often linked to the body adjusting to weight loss, metabolic changes, or the overall treatment journey
If the manufacturer can choose the way those data are presented the manufacturer can effectively rig the outcome. Tan and intervenor lawyers Erin Murphy, for Lilly, and Benjamin Block, for Novo, pushed back hard, saying the agency asked dozens of detailed follow-up questions, demanded extra data and looked up and down the entire supply chain, from manufacturers to wholesalers and pharmacies
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