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Moreover, intrauterine devices (IUD) releasing levonorgestrel are a very suitable option for cases with adenomyosis and increased risk for thrombotic conditions for whom systemic therapy could not be advisable [61, 62] (e.g., women above 40 years old, increased BMI, increased risk for estrogen-dependent diseases such as breast cancer or endometrial hyperplasia)

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10.1136/bcr-2017-220928 256

Role in KLOW KPV gives KLOW a dedicated inflammation-control layer for rosacea-pattern, flushing-prone, post-procedure, or otherwise reactive skin

Interestingly, TRIM37 mutants identified in MUL patients also lead to infertility in mouse models ( FIN major and G322V)

It wont reverse advanced joint damage or change bone structure