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Semaglutide should be discontinued at least 2 months before a planned pregnancy, as weight loss is not recommended during pregnancy
This usually happens once appetite, weight, and side effects level out after moving through the standard dose escalation schedule
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It is still of note that with the excessive number of articles that were produced from the initial search, only 32 articles truly discussed the perioperative risks and management of patients taking GLP-1 RAs and undergoing anesthesia/sedation
Our guide to the best time to take your tirzepatide shot and the best time to take a GLP-1 shot cover the timing considerations in full
However, many companies rely on external partners for downstream steps, in which case the shift to an oral format is less about capital investments and more about simplifying their CMO networka move which could lower both costs and operational risks
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