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It is important to note that if ED develops or worsens during GLP-1 therapy, this is more likely related to the underlying conditions being treated (diabetes, obesity, cardiovascular disease) or other concurrent factors rather than the medication itself

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Guan B, Chen Y, Yang J, Yang W, Wang C

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Nausea is typically transient and can be minimised through gradual dose titration

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Regulatory Information Disclaimer: Statements in this article regarding FDA actions, the 503B Bulks List, drug shortage status, and the federal regulatory framework for compounded GLP-1 medications reflect FDA published guidance current as of May 2026

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However, if you'd rather avoid the stimulant, opt for caffeine-free supplements instead

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