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Real-World Effectiveness Analysis of Switching From Liraglutide or Dulaglutide to Semaglutide in Patients With Type 2 Diabetes Mellitus: The Retrospective REALISE-DM Stud

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(47,48) A relationship between the level of expression of CYP450 and the amount of DNA adducts has been reported

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In the most optimistic scenario, the use of GLP-1 agonists could lead to what we call virtue spirals. In these spirals, weight loss could lead to: Increased physical activity Healthier food choices Sustained weight management This positive feedback loop could influence more than just diet and exercise