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Food sits in the stomach longer, stretching the gastric wall and activating vagal afferent fibers that relay signals back to the brainstem nausea centers

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For patients who struggle with cravings, large portions, or frequent hunger, semaglutide may make it easier to follow a nutrition plan

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[5] [6] During this washout period, you may notice a gradual return of appetite and changes in satiety signals that were previously suppressed

[PMID: 4043038] PubMed record related to this compound for laboratory literature review