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The medication is usually taken in the morning or evening, with or without food
Cortisol peaks in the early morning the so-called cortisol awakening response and gradually declines through the day
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Results also depend on proper dosing and gradual titration under medical supervision
This increase of FFA in the liver and circulation results in hypertriglyceridemia, pronounced in the postprandial period, and fasting dyslipidemia leading to insulin resistance, obesity, and unfavorable changes to the cardiometabolic profile [10, 11]
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