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While many get enough from food, deficiencies are common, especially among vegans, older adults, and those with absorption issues

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Overdoing it can occasionally lead to side effects like nerve irritation (with too much B6), skin flushing (from high-dose B3), or digestive upset

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Reiner 45 found that it was difficult to measure the rate of dilution of sclerosing solutions in the rabbit ear vein because of the greater number of collaterals and rapid blood flow caused by the thermoregulatory nature of the ear