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Clin Sci (Lond) 109:243256
Pipe, S
Their findings revealed that CPT1A, a pivotal regulator of fatty acid metabolism, is overexpressed in HR+ tumors and is necessary for promoting cell proliferation, survival, and the formation of colonies and mammospheres (124)
On the other hand, expression levels of hepatic Cpt1a, Ppara, Hmcs2 and Fgf21 , and circulating ketone bodies and FGF21 found highly elevated at 72 h in G49-treated mice are indicative of the contribution of FFA catabolism and ketogenesis to the lipid clearance
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