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Alcohol can also intensify the gastrointestinal side effects of GLP-1 medications, including nausea and acid reflux
Aim for a minimum of 64 ounces of water daily, more if you exercise intensely
It took almost two decades to overcome the challenges of early versions (the median time between target discovery and drug approval has been 25 years ): Shorter half lives: the early version of GLP1s didnt last very long (broken down in GI tract) so people had to take them 2x per day Less Effective: Saxenda, an early GLP1 injectable, resulted in 7-9% weight loss compared to current GLP1s/GIPs that are showing 15%, 17%, 22% and 25% average weight loss (pending drug, dose, phase of trial, population tested)
Some patients may misinterpret other sensations (such as nausea, anxiety, or habitual eating cues) as hunger
There are also targeted nutrition strategies, like making nonstarchy vegetables the focus of your plate, eating lean protein and drinking water before meals, that can help protect against weight regain