Endocrine and Metabolic Science
39 As shown in the LEADER study (NCT01179048), the secondary composite outcome of persistent doubling of the serum creatinine level, new-onset persistent macroalbuminuria, end-stage renal disease or death due to renal disease occurred significantly less frequently in the treatment group than in the placebo group, with a hazard ratio of 0.78
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How can I manage the side effects
The accurate term is triple hormone receptor agonist, since it acts on the GIP, GLP-1, and glucagon receptors at the same time