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Translating a 15 mg/kg murine dose directly to humans underscores a severe translational gap in the source paper

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TB-500 complements these findings with data suggesting effects on myogenesis, muscle fiber regeneration, and wound repair, particularly through its role in actin regulation and vascular endothelial growth factor (VEGF) expression

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Levels of trkA and BDNF mRNA, but not NGF mRNA, fluctuate across the estrous cycle and increase in response to acute hormone replacement

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