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Adipocyte inflammation is the primary driver of hepatic insulin resistance in a human iPSC-based microphysiological system

There are 100s of PTMs, and many are part of an elaborate system within a cell to respond to both external (hormones, neurotransmitters, nutrients, metabolites) and internal chemical signals

(v) less compact bundles of intermediate filaments

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Prorenin Receptor Blockade Inhibits Development of Glomerulosclerosis in Diabetic Angiotensin II Type 1a Receptor-Deficient Mice