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The appropriate covariance structure (compound symmetry, autoregressive, variance components, or unstructured) was selected, based on the lowest Akaike information criterion (AICC)

The results demonstrate that metformin significantly alters the abundance of specific microorganisms, with certain microbial populations showing a marked decrease, while others increase, indicating a profound impact of metformin on the gut microbiome

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This age-related NAD+ depletion has prompted interest in NAD+ supplementation strategies to support cellular metabolism and possibly counteract aspects of aging

1 As a result, GLP drugs are increasingly being recommended not only for managing blood sugar but also for protecting heart health