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The meta-analysis assessed the risk of SI/B comparing GLP-1 RA medications to placebo in 91 placebo-controlled GLP-1 RA medication trials enrolling 107,910 patients, including 60,338 treated with a GLP-1 RA and 47,572 treated with placebo

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For a once-weekly peptide like semaglutide where consistent dosing drives therapeutic response, these errors accumulate over the life of the vial

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