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Vial fell or was shaken accidentally If a reconstituted vial was shaken vigorously (dropped, thrown in a bag, held by a toddler), some peptide degradation may have occurred

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Arthritis, one of the leading causes of joint pain can also be worsened due to deficiency of Vitamin B12

It really depends on what your doctor recommends based on your individual situation

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Folate, vitamin B6, and vitamin B12 are all required for the conversion of homocysteine into the sulfur-containing amino acid methionine