The daily reality of unpredictable crashes, debilitating brain fog, and profound fatigue is completely valid, even when standard medical tests fail to capture the depth of the dysfunction
Studies have reported low serum folate levels in 15% to 38% of patients with depression and in at least 56% of patients with affective disorders (65)
However, you can manage its flare ups and severity through lifestyle changes and medicines
PMID: 56 ZingkouEMedoroADavinelliSSasoLSotiropoulouGPampalakisG
These include -linolenic acid (C 18:3), which is a precursor of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and linoleic acid (C 18:2), the precursor of arachidonic acid (AA) (220, 221)
Carnitine palmitoyltransferase-1 up-regulation by PPAR-/ prevents lipid-induced endothelial dysfunction