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One of the most common side effects reported for all GLP-1R agonists is malaise ( 5 Future directions and summary As summarized previously, GLP-1R, and to some extent the peptide itself, influences the behavioral and neurochemical outcomes of alcohol and addictive drugs, such as nicotine, opioids, amphetamine, and cocaine

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REAL-WORLD EVIDENCE ON GLP-1 RAs AND LIVER OUTCOMES Beyond randomized controlled trials, emerging real-world data from large observational cohorts and healthcare databases provide important insights into the long-term effectiveness and safety of GLP-1 RAs in patients with MASLD and type 2 diabetes

Diabetes, obesity, peripheral arterial disease, cancer, and substance use can impact both the incidence of wounds as well as the wound healing process

improved collagen organization and tensile strength (PMID: 21030672) Gastrointestinal: Protection against NSAID-induced ulcers, IBD models, fistula healing in preclinical studies (PMID: 31158953) Nerve: Enhanced sciatic nerve regeneration

Gut Microbes 14 , 2009297 (2022)