The fact that retatrutide passed its Phase 1 and Phase 2 trials means researchers deemed it safe enough for large-scale human testing
The ADA/EASD recently published a 2019 update to the 2018 consensus report
Together, these dynamics define a market that is expanding in complexity while also signaling important opportunities for system-level improvements
However, they can be unpleasant for some patients, affecting their ability to tolerate and adhere to the therapy
Forty-two percent of those who were currently using GLP-1s said losing weight on these medications requires the same willpower as traditional methods, and 15% said it takes even more
Masheb & White, 2012), and a subset of these patients report significant weight loss and symptoms of starvation (Bodell & Keel, 2015)