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Efficacy and safety of GLP-1 receptor agonists as add-on to SGLT2 inhibitors in type 2 diabetes mellitus: a meta-analysis

Direct drug effects, if any, seem to favor improved motility and possibly morphology

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The review highlights FOXO4-DRI's unique mechanism as a peptide-based senolytic with high selectivity for senescent cells, while noting challenges for clinical translation including peptide delivery and stability

Studies show they help teens lose 5-16% of body weight when combined with lifestyle changes

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