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Originally developed to treat diabetes, tirzepatide is safe and highly effective for long-term weight loss and weight management
The secondary outcomes included the association with the individual components of major adverse cardiovascular events (myocardial infarction, ischaemic stroke, cardiovascular mortality), heart failure, and all cause mortality
Areas of study include downstream IGF-1 pathway interactions and receptor selectivity modeling
All patients completed clinical assessments except one SZ patient who refused the PANSS and BACS assessments, and one BP patient who refused the PANSS assessment