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Results: Mean (range) baseline characteristics of the 957 treated subjects (35% male) were: age 47 (18-86) years, weight 111 (70-244) kg, body mass index 39 (30-80) kg/m2, NFS -0.49 (-4.70 to 4.66), and FIB-4 0.72 (0.14-3.31)
General mitochondrial trifunctional protein (TFP) deficiency as a result of either alpha- or beta-subunit mutations exhibits similar phenotypes because mutations in either subunit alter TFP complex expression and subunit turnover
Australian Stock Exchange filing (2007) 10
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Its main function is to inhibit xanthine oxidase