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The antenna catches the signal, triggers a chain reaction inside the cell (called the MAPK/ERK cascade) and the cell receives the instruction: Start dividing and build a new vessel. Hsieh et al
doi: 10.1126/SCIIMMUNOL.AAZ6563 20 KomuczkiJTuzlakSFriebelEHartwigTSpathSRosenstielPet al
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By bridging these insights, we aim to elucidate why modulating immune cell metabolism and mitochondria is a promising new frontier and how it could transform organ protection in surgery moving beyond generalized anti-inflammatory approaches towards precise immunometabolic therapy that DAMPens harmful inflammation without crippling host defenses
