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Persistent or severe vomiting or abdominal pain whilst on GLP-1 therapy may suggest pancreatitis and requires urgent medical attention
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While GLP-1R agonists have demonstrated cardiovascular benefits in clinical trials, including reduced rates of major adverse cardiovascular events (MACE) in T2DM patients, their antithrombotic efficacy is generally considered less potent than that of traditional antithrombotic agents
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These drugs slow gastric emptying and alter gut motility, which are fundamental to their therapeutic action, although these effects may diminish somewhat over time
