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BMC Complement Altern Med

Whether comparable propagation dynamics occur in three-dimensional tissues, where extracellular matrix constraints, variable cell density, heterogeneous antioxidant buffering, and local repair mechanisms are likely to shape spread, remains insufficiently resolved and presents a translational gap

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Furthermore, abnormalities in the Nrf2-p62 pathway also impair autophagy in vitiligo melanocytes under oxidative stress [28, 29]

Frozen storage ( 20 C, and preferably lower for long-term): Recommended for extended timelines, with vials kept well sealed to limit moisture uptake and oxidative degradation