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When paired with berberine, the combination can: This synergistic action makes the berberinechromium pairing especially popular for individuals managing prediabetes, type 2 diabetes, or metabolic syndrome, where insulin resistance and abnormal cholesterol levels are common challenges
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They are contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)
Journal of experimental pharmacology , 4 , 149155