It's a more meaningful decision than it first appears vial size affects cost-per-milligram, reconstitution concentration, and how much usable research window you get before reconstituted material should be discarded
Zhang A, Liu Q, Xiong Y, Li J, Xu Y, Song H, et al
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Effects of low- and high-density lipoproteins on the proliferation of human breast cancer cells in vitro: differences between hormone-dependent and hormone-independent cell lines
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That's why it is often associated with improved endurance and reduced muscle fatigue