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One of the more recent developments is the introduction of glucagon-like peptide-1 receptor agonists (GLP-1 RAs)

Yusta B, Baggio LL, Estall JL, Koehler JA, Holland DP, Li H, Pipeleers D, Ling Z, and Drucker DJ

A 2010 New England Journal of Medicine trial by Falutz et al

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If you are trying to gain muscle with minimal fat accumulation, a very low dose (0.5-1mg) might help manage appetite enough to prevent the excessive caloric surplus that leads to unnecessary fat gain

The benefits of these medications extend to the kidneys, liver, and potentially the brain, immune system, and gut