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Meanwhile, in January 1996 the first rodent study suggested that GLP-1 could be a central regulator of feeding behavior and satiety based on intracerebroventricular injection studies [4], but soon thereafter the results of other rodent studies using peripherally injected GLP-1 argued against an appetite effect [5]
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Many studies have revealed numerous additional functions of glucagon in the brain, liver, heart, and adipose tissue in addition to its well-known function in regulating blood sugar levels [30,31,32]
Patients with type 2 diabetes were more likely to experience a reduction in pain from high-dose Acetyl L-Carnitine than were patients with type 1 diabetes
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