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and patients with acute abdominal conditions, active IBD such as colitis, neutropenia (either present or anticipated following chemo- or radiotherapy), or active intestinal perforation and leakage (543)

Any use outside its licensed indication would be considered off-label prescribing, which requires careful clinical justification and informed patient consent

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Her total cost over twelve months including maintenance is tracked in the hidden-cost table further down this page so you can see the real annualised number rather than just the headline price