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Deoxycholic acid-induced gut dysbiosis disrupts bile acid enterohepatic circulation and promotes intestinal inflammation

Studies show it has multiple functions: regulating insulin sensitivity and metabolic homeostasis, preventing age- and high-fat diet-induced insulin resistance/obesity in mice, protecting the heart in cardiovascular diseases via relevant pathways, and reducing inflammation when intraperitoneally administered

doi: 10.1053/j.gastro.2010.09.038 105 XiaoM.-W.LinS.-X.ShenZ.-H.LuoW.-W.WangX.-Y

Overlapping protective roles for glutathione transferase gene family members in chemical and oxidative stress response in Agrobacterium tumefaciens

For instance, adverse events reported after intravenous glutathione included nausea, vomiting, chills, low blood pressure, breathing difficulty, possible bloodstream infection