The 2.5 mg dose is better called the low-dose starter, because it is the labeled start and now has short direct non-diabetic data behind it. Microdosing has been used for tolerability testing, metabolic-marker support, step-down protocols, and maintenance, not for proven long-term obesity outcomes
Most evidence comes from laboratory and animal studies rather than controlled human trials, which means benefits remain investigational
Metoclopramide is the only FDA-approved drug for gastroparesis, and it carries a black box warning for tardive dyskinesia risk with long-term use
If you have blood in stool, anemia, or a strong family history of IBD, dont self-label
You can purchase Thorne Craving and Stress Support at Integrative Health, 208-799-3333
Very high doses (such as those used for cyanide poisoning) should be used with caution and only if the potential benefit outweighs the risk