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Glutamine is a neutral amino acid and thus does not induce a negative charge burden in the mitochondrial matrix, which is already more negatively charged than the cytosol

Astrocytes, the major glial support cells in the CNS, are indispensable in the regulation of GSH homeostasis

They also support the antioxidant system by enhancing the activity of enzymes such as APX and GR, which mitigate HO-induced membrane damage

It's a signaling molecule focused on tissue repair and protection

Some experimental results suggest significant increases in circulating IGF-1, which is thought to act as a downstream mediator of growth hormone activity

Enhanced Klotho availability protects against cardiac dysfunction induced by uraemic cardiomyopathy by regulating Ca(2+) handling