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Abstract The gold standard for studies of glutamateglutamine (GABA) cycling and its connections to brain biosynthesis from glucose of glutamate and GABA and their subsequent metabolism are the elegant in vivo studies by 13 C magnetic resonance spectroscopy (NMR), showing the large fluxes in the cycle
This is also exemplified by active GABAergic signaling at early neonatal stages (Lauder et al., 1986), and glutamatergic activation of synchronized spike waves in 35-day-old rats (Seki et al., 2012)
Current Chemical Biology 8(2):89-99. [doi.org]
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A key concern lies in the black box nature of many ML algorithms
17 DobnigH.TurnerR
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