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And oil red O staining showed that GLP-1 had no significant effect on lipid accumulation

The Food and Drug Administration approved Ozempic in 2017 for adults with Type 2 diabetes

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Compounded and FDA-approved medications are not interchangeable

On the other hand, although both HNF4-depleted HepG2 cells and SNU449 cells displayed reduced proliferation, as evident by a reduced fraction of cells in S-phase compared to control HepG2 cells (Supplementary Fig