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Acute injuries: Noticeable improvements within 1-2 weeks Chronic conditions: Gradual improvement over 3-6 months Degenerative diseases: Variable response, often requiring longer treatment durations Table: Condition-Specific Response Timelines Patch Material and Cell Type Influences The type of stem cell patch and cells used matters a lot

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In melasma, 4% niacinamide has led to a 62% reduction of hemi-MASI (hMASI) after 8 weeks [45]