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6) mice were significantly higher than levels in wild-type mice

For a patient at 113 kg, that is 15 kg over 72 weeks, enough to reverse prediabetes in many cases, meaningfully reduce blood pressure, and improve sleep quality

The bottom line on taking tirzepatide 2 days early Taking tirzepatide two days early is generally safe as a one-time event if you maintain at least 72 hours (three full days) between doses