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INTRODUCTION Vitamin B12 is essential for DNA synthesis, red blood cell formation, and neurologic function[] and is also involved in the metabolism of fat and carbohydrate.[] The clinical manifestations of vitamin B12 deficiency are the effects of depletion on multiple systems, and their severity varies greatly

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Avoid complete immobilization unless specifically indicated

The mechanical stress and shearing forces can break the delicate peptide bonds and denature the protein, rendering it biologically inactive

At postoperative day 28, voiding through fistula in controls (fecaluria) ( c ) and a normal voiding in BPC 157-rats ( b )